GLIOFORCE Targeting Cellular Biomechanics to block Tumour Cell Invasion

Duration
01.08.2026–31.07.2030

GLIOFORCE will investigate how biophysical forces contribute to the spread of invasive cancer. By integrating state-of-art in vivo 3-photon imaging and quantum biosensors with in silico biomechanics
modelling and computational drug design, GLIOFORCE aims to identify and target cancer-specific biomechanical vulnerabilities to block invasion and ultimately improve patient outcomes.

Contact

Primary objective:

To build a strong and lasting interdisciplinary framework that describes, models, and targets biomechanical forces during cancer cell invasion.

Secondary objectives:

  • Integrate advanced imaging, genetics and biomechanics to measure and manipulate cancer invasion.
  • Develop predictive in silico models for cancer cell invasion incorporating biomechanical parameters.
  • Explore advanced quantum emitters as innovative reporters of biomechanical forces.
  • Design and test new chemical compounds targeting cancer-specific biomechanical vulnerabilities.
  • Build lasting bridges between biomedicine, physics, engineering and pharmacy environments.
  • Raise awareness amongst clinicians and pathologists, incorporate biomechanics elements in curricula for students, and in advanced courses to train the next generation of scientists.

Participants

Funding

GLIOFORCE?is financed by UiO:Life Science

Published Nov. 5, 2025 8:33 AM - Last modified Mar. 16, 2026 10:09 AM